| Rank | Programs | Network | Households, 000 | |
| 1 | American Idol – Tuesday | FOX | 2153 | |
| 2 | American Idol – Wednesday | FOX | 1945 | |
| 3 | Heroes | NBC | 1832 | |
| 4 | Lost | ABC | 1793 | |
| 5 | Fringe | FOX | 1602 | |
| 6 | House | FOX | 1454 | |
| 7 | The Mentalist | CBS | 1445 | |
| 8 | Survivor: Gabon | CBS | 1396 | |
| 9 | Grey’s Anatomy – Thur 9PM | ABC | 1358 | |
| 10 | Bones | FOX | 1331 | |
| Source: Nielsen | ||||