| Rank | Title | Distributor | Release Date | |
| 1 | Iron Man | Paramount Home Entertainment | 9/30/08 | |
| 2 | I Am Legend | Warner Home Video | 3/18/08 | |
| 3 | Alvin and the Chipmunks | Twentieth Century Fox Home Ent | 4/1/08 | |
| 4 | Enchanted | Disney/Buena Vista Home Video | 3/18/08 | |
| 5 | National Treasure 2 : Book of Secrets | Disney/Buena Vista Home Video | 5/20/08 | |
| 6 | Wall-E | Disney/Buena Vista Home Video | 11/18/08 | |
| 7 | Indiana Jones and the Kingdom of the Crystal Skull | Paramount Home Entertainment | 10/14/08 | |
| 8 | Sex and the City – The Movie | Warner Home Video | 9/23/08 | |
| 9 | Bee Movie | Paramount Home Entertainment | 3/11/08 | |
| 10 | American Gangster | Universal Home Entertainment | 2/19/08 | |
| Source: Nielsen | ||||